Endocrine Abstracts

Background: Worldwide, bread is one of the most consumed foodstuff. White bread is made of white flour and process involves the exclusion of bran and embryo. On contrary, these are preserved in whole wheath. Compared the whole grain bread, most commercial white wheat breads contain little dietary fiber and it is assumed to cause more drastic rise and fall on glucose and insulin levels.Objective: Aiming to investigate 3-hour effect of two different type o...

IntroductionPituitary adenomas generate 10–15% of primary brain tumors. Most of these adenomas are benign and orginate from the epithelial cells of the adenohypophysis. Pituitary adenomas can occur in all age groups, but most common in the third and sixth decades. In this study, we are investigated the demographic characteristics of pituitary adenomas and non-adenoma lesions that admission to the Bozyaka Education and Research Hospital Endocrinology...

Introduction: Diabetes Mellitus is a significant metabolic condition characterized by its widespread occurrence and associated complications. Reports indicate that DM impacts 25% of the global population. The way individuals handle their existing illnesses throughout their lifetimes is crucial in terms of uncertainty and self-care behaviors within chronic diseases such as DM. The connection between individuals’ physiological parameters (HbA1c etc.) and uncertainty, as wel...

Introduction: Polycystic ovary syndrome (PCOS) stands out as one of the prevalent endocrine disorders affecting women in their reproductive years, impacting 8-13% of females as per World Health Organization (WHO) statistics. This condition has significant repercussions on a woman’s sense of self, mental well-being, and overall life quality. While individuals with PCOS often grapple with anxiety and sadness throughout the diagnosis and treatment phases, external factors ca...

Vitamin D binding protein (VDBP) has a critical role in orchestrating optimal vitamin D homeostasis and bioavailability. VDBP has been implicated in modulating the gene expression of amino-transporters within the placenta and might thus control the transfer of amino acids to neonates during in utero development. We hypothesize that dyshomeostasis of VDBP could lead to adverse metabolic profiles and low birth weight in neonates. VDBP genetic polymorphisms steer the uni...

Evaluation of Laboratory Findings of Primary Hyperparathyroidism in Geriatric PatientsBackground: Primary hyperparathyroidism (PHPT) is an endocrine disease characterized by excessive secretion of parathormone (PTH) from one or more parathyroid glands. In recent studies, it has been reported that the PHPT clinic has turned into a largely asymptomatic disease in recent years. There are few studies on the effect of aging on laboratory find...

Introduction: Exosomes are nanoparticles containing bioactive molecules reflecting individual physiological status, regulating metabolism, and repairing damaged tissues. Exosomes are extracellular vesicles with nano-sized features (30-150 nm) involved in cell-to-cell communication and maintaining homeostasis. The function of exosomes is different according to their cargo and they can contain lipids, proteins and nucleic acids. Exosomes originating from mammalian cells as well ...

Aim: Thyroid hormones have many effects on the cardiovascular system. May studies have showed that apparent or subclinical hypothyroidism increase the risk of hypertension hyperlipidemia and so lead to atherosclerosis susceptibility. This risk can be reduced by treatment. But, studies on the relationship between thyroid function tests and cardiovascular risk in euthyroid subjects are contradictory. This study was designed to investigate the effect of TSH, free T3, f...

Diabetes insipidus (DI) is a disorder that characterized by producing large volume of urine for daily due to the problems at the arginine vasopressin (AVP-NPII), aquaporin 2 (AQP2) and arginine vasopressin receptor 2 (AVPR2) genes. These problems can be inherited or acquired. Among these genes, AVPR2 is a G protein coupled receptor and most of the inherited type of DI are caused by mutations in AVPR2 gene. Mutations can cause improper folding of the receptor protein and this s...

Aim: There are studies showing that Hashimoto’s thyroiditis (HT) progresses more rapidly, thyroid echogenicity is lower and thyroid autoantibodies are higher titer positive in immunoglobulin G4 (IGg4) positive patients.But a small number of studies that do not support this data have also been published.We planned this study to evaluate the findings of IgG4 (+) Hashimoto’s thyroiditis cases.Materials and methods: New diagnosis without treatment ...